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dc.contributor.authorAmaraporn Rerkasemen_US
dc.contributor.authorSarah E. Maessenen_US
dc.contributor.authorAntika Wongthaneeen_US
dc.contributor.authorSakda Pruenglampooen_US
dc.contributor.authorAmpica Mangklabruksen_US
dc.contributor.authorPatumrat Sripanen_US
dc.contributor.authorJosé G.B. Derraiken_US
dc.contributor.authorKittipan Rerkasemen_US
dc.description.abstractWe examined the associations between caesarean section (CS) delivery and cardiovascular risk factors in young adults in Thailand. Participants were 632 offspring from a birth cohort in Chiang Mai (Northern Thailand), born in 1989–1990 and assessed in 2010 at a mean age of 20.6 years, including 57 individuals (9.0%) born by CS and 575 born vaginally. Clinical assessments included anthropometry, blood pressure (BP), carotid intima-media thickness, and fasting blood glucose, insulin, and lipid profile. Young adults born by CS had systolic BP (SBP) 6.2 mmHg higher (p < 0.001), diastolic BP 3.2 mmHg higher (p = 0.029), and mean arterial pressure (MAP) 4.1 mmHg higher (p = 0.003) than those born vaginally. After covariate adjustments, SBP and MAP remained 4.1 mmHg (p = 0.006) and 2.9 mmHg (p = 0.021) higher, respectively, in the CS group. The prevalence of abnormal SBP (i.e., pre-hypertension or hypertension) in the CS group was 2.5 times that of those born vaginally (25.0% vs 10.3%; p = 0.003), with an adjusted relative risk of abnormal SBP 1.9 times higher (95% CI 1.15, 2.98; p = 0.011). There were no differences in anthropometry (including obesity risk) or other metabolic parameters. In this birth cohort in Thailand, CS delivery was associated with increased blood pressure in young adulthood.en_US
dc.titleCaesarean delivery is associated with increased blood pressure in young adult offspringen_US
article.title.sourcetitleScientific Reportsen_US
article.volume11en_US Instituteen_US University School of Medicineen_US Universiteten_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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