Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/76183
Title: Association of cardio-ankle vascular index and future major adverse cardiovascular events in older adults living with HIV
Authors: Amaraporn Rerkasem
Arunrat Tangmunkongvorakul
Linda Aurpibul
Patumrat Sripan
Wason Parklak
Sothida Nantakool
Kriengkrai Srithanaviboonchai
Kittipan Rerkasem
Authors: Amaraporn Rerkasem
Arunrat Tangmunkongvorakul
Linda Aurpibul
Patumrat Sripan
Wason Parklak
Sothida Nantakool
Kriengkrai Srithanaviboonchai
Kittipan Rerkasem
Keywords: Medicine
Issue Date: 1-Jan-2022
Abstract: Increased arterial stiffness is an indicator of cardiovascular disease (CVD) and death in the general population. The cardio-ankle vascular index (CAVI) is a novel method for measuring arterial stiffness. This study investigated the utility of CAVI as a prognostic indicator of CVD and death in older adults living with HIV(OALHIV). Patients aged ≥50 taking antiretroviral treatment with no history of cardiovascular events enrolled from multiple centers in Chiang Mai, Thailand. Participants (N = 347) who underwent CAVI were followed up for five years. The primary endpoint was major adverse cardiovascular events (MACE): a composite of total deaths and hospitalizations due to myocardial infarction, coronary revascularization, stroke, and heart failure. Cox regression analysis determined between normal (<8) and high (≥8) CAVI against the incidence of MACE. Forty-five participants (13.0%) were diagnosed with MACE. The risk of MACE was more significant in high CAVI than normal CAVI (adjusted HR = 2.11, 95% confidence interval 1.06–4.20, p = 0.033). In OALHIV, CAVI was an independent prognosis of MACE, in addition to conventional CVD risk factors. CAVI-assisted to help identify high-risk patients showed the benefit of further evaluation and more intensive therapy to prevent CVD and death.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85132669561&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/76183
ISSN: 13600451
09540121
Appears in Collections:CMUL: Journal Articles

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