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dc.contributor.authorSopit Phetsangen_US
dc.contributor.authorDuangruedee Khwannimiten_US
dc.contributor.authorParawee Rattanakiten_US
dc.contributor.authorNarong Chanleken_US
dc.contributor.authorPinit Kidkhunthoden_US
dc.contributor.authorPitchaya Mungkornasawakulen_US
dc.contributor.authorJaroon Jakmuneeen_US
dc.contributor.authorKontad Ounnunkaden_US
dc.description.abstractA novel copper (II) ions [Cu(II)]-graphene oxide (GO) nanocomplex-modified screen-printed carbon electrode (SPCE) is successfully developed as a versatile electrochemical platform for construction of sensors without an additionally external redox probe. A simple strategy to prepare the redox GO-modified SPCE is described. Such redox GO based on adsorbed Cu(II) is prepared by incubation of GO-modified SPCE in the Cu(II) solution. This work demonstrates the fabrications of two kinds of electrochemical sensors, i.e., a new label-free electrochemical immunosensor and non-enzymatic sensor for detections of immunoglobulin G (IgG) and glucose, respectively. Our immunosensor based on square-wave voltammetry (SWV) of the redox GO-modified electrode shows the linearity in a dynamic range of 1.0–500 pg.mL−1 with a limit of detection (LOD) of 0.20 pg.mL−1 for the detection of IgG while non-enzymatic sensor reveals two dynamic ranges of 0.10–1.00 mM (sensitivity = 36.31 μA.mM−−2) and 1.00–12.50 mM (sensitivity = 3.85 μA.mM−−2) with a LOD value of 0.12 mM. The novel redox Cu(II)-GO composite electrode is a promising candidate for clinical research and diagnosis.en_US
dc.titleA Redox Cu(II)-Graphene Oxide Modified Screen Printed Carbon Electrode as a Cost-Effective and Versatile Sensing Platform for Electrochemical Label-Free Immunosensor and Non-enzymatic Glucose Sensoren_US
article.title.sourcetitleFrontiers in Chemistryen_US
article.volume9en_US Institute of Technology, Nagaoka Collegeen_US Universityen_US Mai Universityen_US Light Research Institute (Public Organization)en_US
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