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dc.contributor.authorAmro M. Solimanen_US
dc.contributor.authorTeoh Seong Linen_US
dc.contributor.authorPasuk Mahakkanukrauhen_US
dc.contributor.authorSrijit Dasen_US
dc.description.abstract© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Multiple myeloma (MM) is a cancerous bone disease characterized by malignant transformation of plasma cells in the bone marrow. MM is considered to be the second most common blood malignancy, with 20,000 new cases reported every year in the USA. Extensive research is currently enduring to validate diagnostic and therapeutic means to manage MM. microRNAs (miRNAs) were shown to be dysregulated in MM cases and to have a potential role in either progression or suppression of MM. Therefore, researchers investigated miRNAs levels in MM plasma cells and created tools to test their impact on tumor growth. In the present review, we discuss the most recently discovered miRNAs and their regulation in MM. Furthermore, we emphasized utilizing miRNAs as potential targets in the diagnosis, prognosis and treatment of MM, which can be useful for future clinical management.en_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemical Engineeringen_US
dc.subjectComputer Scienceen_US
dc.titleRole of micrornas in diagnosis, prognosis and management of multiple myelomaen_US
article.title.sourcetitleInternational Journal of Molecular Sciencesen_US
article.volume21en_US of Albertaen_US Kebangsaan Malaysiaen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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