Five-and ten-year survival of squamous cell carcinoma of the head and neck in northern Thailand: A multivariate analysis

Abstract

© The Author(s), 2020. Published by Cambridge University Press. Aim:To report 5-and 10-year overall survival (OS) outcomes of squamous cell carcinoma of the head and neck and identify prognostic factors.Methods:Data on 2,095 patients at Maharaj Nakorn Chiang Mai Hospital, Thailand between 2007 and 2014 were analysed using the Kaplan-Meyer method to estimate 5-and 10-year OS rates. Cox proportional hazard regression models were applied to assess the independent prognostic factors of survival.Results:8·7% had hypopharyngeal cancer, 19·7% laryngeal, 53·3% oral cavity and 18·3% oropharyngeal. Two-thirds of the patients had locally advanced stage (III-IVB). Five-and ten-year OS rates were 30·1 and 22·8%, respectively.Conclusions:Cancer site, stage and age at diagnosis were associated with mortality, highlighting the importance of prevention and early detection.