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http://cmuir.cmu.ac.th/jspui/handle/6653943832/56666| Title: | Voltage-gated sodium channels assemble and gate as dimers |
| Authors: | Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes |
| Authors: | Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes |
| Keywords: | Biochemistry, Genetics and Molecular Biology;Chemistry;Physics and Astronomy |
| Issue Date: | 1-Dec-2017 |
| Abstract: | © 2017 The Author(s). Voltage-gated sodium channels are expressed in excitable tissues and mutations have been linked to cardiac arrhythmias and channelopathies. Here the authors show that the sodium channel α-subunits interact to form a dimer and gate as dimer and that this functional dimerisation is conserved. |
| URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037870387&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/56666 |
| ISSN: | 20411723 |
| Appears in Collections: | CMUL: Journal Articles |
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