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dc.contributor.authorSeyed Hossein Hoseinifaren_US
dc.contributor.authorAlireza Ahmadien_US
dc.contributor.authorMohsen Khalilien_US
dc.contributor.authorMojtaba Raeisien_US
dc.contributor.authorHien Van Doanen_US
dc.contributor.authorChristopher Marlowe Caipangen_US
dc.description.abstract© 2017 John Wiley & Sons Ltd The aim of the present study was to study the effects of different prebiotics (galacto-, fructooligosaccharide and inulin) on immune response and oxidative stress of common carp (Cyprinus carpio) fingerlings at the molecular level. A total number of 240 fish (13.85 ± 0.85 g) were supplied and randomly stocked in twelve fiberglass tanks (20 specimens per tank). Fish were fed a basal formulated diet (Control) or basal diet supplemented with equal level (2%) of different prebiotics (four treatments repeated in triplicated) for 8 weeks. At the end of feeding trial, the expression of immune-related genes (interleukin 1 beta [IL-1β], IL-8, IL-10, lysozyme [LYZ], tumour necrosis factor alpha [TNF-α] and transforming growth factor beta [TGF-β]) were determined in head kidney and intestine tissues and the expression of antioxidant-related genes (glutathione S-transferase [GST-α], glutathione reductase [GR] and glutathione peroxidase genes [GPX]) were studied in intestine. The results revealed that dietary administration of prebiotics modulated the expression of immune-related genes and the degree of expression was affected by the type of prebiotics and the organ that was used for analyses. Also, evaluation of antioxidant genes expression showed that GSTα and GR expression levels increased as a result of feeding common carp with the prebiotics. According to these findings, it can be concluded that feeding on different prebiotics had altered effects on the expression of immune and antioxidant-related genes.en_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.titleThe study of antioxidant enzymes and immune-related genes expression in common carp (Cyprinus carpio) fingerlings fed different prebioticsen_US
article.title.sourcetitleAquaculture Researchen_US
article.volume48en_US University of Agricultural Sciences and Natural Resourcesen_US University of Medical Sciencesen_US Mai Universityen_US Polytechnicen_US
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