Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorPrapaporn Supraserten_US
dc.contributor.authorKittipat Charoenkwanen_US
dc.contributor.authorSitthicha Siriareeen_US
dc.contributor.authorChalong Cheewakriangkraien_US
dc.contributor.authorJaruwan Saetengen_US
dc.contributor.authorJatupol Srisomboonen_US
dc.description.abstractObjective To evaluate disease-free survival (DFS) after radical hysterectomy and pelvic lymphadenectomy (RHPL) among early-stage cervical cancer patients with single-node involvement versus patients with no nodal involvement. Methods A retrospective review was conducted of the medical records of 843 patients undergoing RHPL at Chiang Mai University Hospital, Thailand, between January 1, 2002, and December 31, 2008. Neoadjuvant chemotherapy was administered when the operative schedule was more than 1 month after diagnosis and adjuvant chemoradiation was administered to high-risk patients. Five subgroups were defined on the basis of pelvic node involvement: group A (0 nodes; n = 706), group B (1 node; n = 65), group C (2 nodes; n = 38), group D (3 nodes; n = 13), and group E (≥ 4 nodes; n = 21). Results The 5-year DFS was comparable for groups A and B (94.3% versus 92.1%; P = 0.454). In groups C, D, and E, the 5-year DFS was 85.9%, 75.0%, and 61.8%, respectively. The survival outcomes for groups A and B were significantly different from those of the other 3 groups (P < 0.001). Conclusion Cervical cancer patients with single-node involvement had comparable survival outcomes to those without nodal metastases; however, patients with multiple node involvement had reduced DFS. © 2012 International Federation of Gynecology and Obstetrics.en_US
dc.titleOutcome of cervical cancer patients with single-node compared with no nodal involvement treated with radical hysterectomy and pelvic lymphadenectomyen_US
article.title.sourcetitleInternational Journal of Gynecology and Obstetricsen_US
article.volume121en_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.

Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.