Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorYoshiyuki Tohnoen_US
dc.contributor.authorSetsuko Tohnoen_US
dc.contributor.authorCho Azumaen_US
dc.contributor.authorNutcharin Ongkanaen_US
dc.contributor.authorPasuk Mahakkanukrauhen_US
dc.contributor.authorTakeshi Minamien_US
dc.contributor.authorPatipath Suwannahoyen_US
dc.contributor.authorKittikun Viwatpinyoen_US
dc.contributor.authorLining Keen_US
dc.description.abstractTo elucidate the compositional changes of the amygdala with aging, the authors investigated age-related differences of elements in human amygdalae. In addition, the relationships between the amygdala and other brain regions were investigated from a viewpoint of elements. After ordinary dissections at Nara Medical University were finished, the amygdalae were removed from the cerebra of the subjects who consisted of 22 men and 23 women, ranging in age from 70 to 101 years. In addition, the hippocampus, dentate gyrus, mammillary body of the limbic system and the caudate nucleus, putamen, and globus pallidus of the basal ganglia were also removed from the identical cerebra. After the brain samples were incinerated with nitric acid and perchloric acid, the element contents were determined by inductively coupled plasma-atomic emission spectrometry. It was found that both the Ca and Mg contents increased significantly in the amygdalae with aging, but the other five element contents (P, S, Zn, Fe, and Na) did not change significantly in the amygdalae with aging. Regarding the relationships among elements, very significant or significant direct correlations were found among the Ca, P, and Mg contents in the amygdalae. To explore the relationships between the amygdala and either other limbic system or basal ganglia, the correlations between seven elements of the amygdala and hippocampus, dentate gyrus, or mammillary body, and between those of the amygdala and caudate nucleus, putamen, or globus pallidus which derived from the identical cerebra, were analyzed with Pearson's correlation. It was found that regarding the four elements of Ca, P, Mg, and Fe, a close relationship existed between the amygdala and hippocampus, globus pallidus, or mammillary body. © 2013 Springer Science+Business Media New York.en_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleAge-related differences and relationships between elements in human amygdala and other limbic system or basal gangliaen_US
article.title.sourcetitleBiological Trace Element Researchen_US
article.volume152en_US Mai Universityen_US Medical Universityen_US Universityen_US Medical Universityen_US
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.

Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.