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Title: An alternative synthesis of (+) - propranolol and (+) atenolol
Authors: Rachaneebhorn Inkum
Aphiwat Teerawutgulrag
Pakawan Puangsombat
Nuansri Rakariyatham
Keywords: Multidisciplinary
Issue Date: 1-Sep-2012
Abstract: Herein, a simple synthesis pathway of beta-blockers starting from allyl amine is presented. This synthesis features the opening of an epoxide ring with phenol derivatives followed by N-alkylation with iso-propylbromide to produce racemic propranolol and atenolol. © 2012 by Maejo University, San Sai, Chiang Mai, 50290 Thailand.
ISSN: 19057873
Appears in Collections:CMUL: Journal Articles

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