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dc.contributor.authorRuangrat Choommongkolen_US
dc.contributor.authorRattana Jongkolen_US
dc.contributor.authorSamran Prabpaien_US
dc.contributor.authorPalangpon Kongsaereeen_US
dc.contributor.authorPuttinan Meepowpanen_US
dc.date.accessioned2018-09-04T06:02:13Z-
dc.date.available2018-09-04T06:02:13Z-
dc.date.issued2012-03-15en_US
dc.identifier.issn1362511Xen_US
dc.identifier.issn09574166en_US
dc.identifier.other2-s2.0-84860307253en_US
dc.identifier.other10.1016/j.tetasy.2012.03.006en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84860307253&origin=inwarden_US
dc.identifier.urihttp://cmuir.cmu.ac.th/jspui/handle/6653943832/51462-
dc.description.abstractSpirocyclopentanone-anthracene adducts, novel antimalarial agents, have been synthesized by employing the racemic and the optically active dimethyl itaconate-anthracene adducts in a reaction with piperine via tandem Michael addition-Dieckmann condensation reactions as the key steps. All adducts exhibited antimalarial activity with IC50values of 3.4-4.7 μg/mL, and importantly displayed non-cytotoxicity to vero cells. © 2012 Elsevier Ltd. All rights reserved.en_US
dc.subjectChemical Engineeringen_US
dc.subjectChemistryen_US
dc.titleSynthesis of racemic and optically active forms of novel antimalarial agents, spirocyclopentanone-anthracene adducts, via tandem Michael addition-Dieckmann condensation reactions as the key stepsen_US
dc.typeJournalen_US
article.title.sourcetitleTetrahedron Asymmetryen_US
article.volume23en_US
article.stream.affiliationsChiang Mai Universityen_US
article.stream.affiliationsMahidol Universityen_US
Appears in Collections:CMUL: Journal Articles

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