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dc.contributor.authorQuang Duy Trinhen_US
dc.contributor.authorNgan Thi Kim Phamen_US
dc.contributor.authorTuan Anh Nguyenen_US
dc.contributor.authorTung Gia Phanen_US
dc.contributor.authorHainian Yanen_US
dc.contributor.authorLe Phuc Hoangen_US
dc.contributor.authorPattara Khamrinen_US
dc.contributor.authorNiwat Maneekarnen_US
dc.contributor.authorYan Lien_US
dc.contributor.authorShoko Okitsuen_US
dc.contributor.authorMasashi Mizuguchien_US
dc.contributor.authorHiroshi Ushijimaen_US
dc.description.abstractSequence and phylogenetic analyses of the rotavirus VP7 gene were performed on 52 human G2 and G4 strains isolated in Japan, China, Thailand, and Vietnam during 2001-2003. All genotype G2 strains included in the study clustered into lineage II of the phylogenetic tree, together with the majority of global G2 strains detected since 1995. The amino acid substitution at position 96 from aspartic acid to asparagine was noted among the emerging or re-emerging G2 rotavirus strains in Japan, Thailand, and Vietnam during 2002-2003. Genotype G4 strains detected in Vietnam grouped into lineage Ia of the phylogenetic tree, whereas Japanese G4 strains clustered in lineage Ic which included emerging G4 strains from Argentina, Italy, Paraguay, and Uruguay. It is noteworthy that an insertion of asparagine was found at position 76 in all the Japanese strains and that its presence might be involved in the emergence of G4 rotavirus in Japan during 2002-2003. © 2010 Wiley-Liss, Inc.en_US
dc.subjectImmunology and Microbiologyen_US
dc.titleSequence analysis of the VP7 gene of human rotaviruses G2 and G4 isolated in Japan, China, Thailand, and Vietnam during 2001-2003en_US
article.title.sourcetitleJournal of Medical Virologyen_US
article.volume82en_US of Tokyoen_US's Hospital No. 1en_US Universityen_US Mai Universityen_US Education Collegeen_US
Appears in Collections:CMUL: Journal Articles

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