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dc.contributor.authorTaridaporn Bunyapaiboonsrien_US
dc.contributor.authorSeangaroon Yoiprommaraten_US
dc.contributor.authorPrasert Srikitikulchaien_US
dc.contributor.authorKitlada Srichomthongen_US
dc.contributor.authorSaisamorn Lumyongen_US
dc.description.abstractSix new oblongolides, W1, W2, X, Y, and Z (1-3, 6, 7) and 2-deoxy-4α-hydroxyoblongolide X (4), and the known compounds oblongolide (8), oblongolides T, C, and Q (5, 9, 10), and (-)-5-methylmellein were isolated from the endophytic fungus Phomopsis sp. BCC 9789. Compound 7 showed anti-HSV-1 activity (IC50 ) 14 μM) and cytotoxic activities against KB, BC, NCI-H187, and nonmalignant (Vero) cell lines with respective IC50 values of 37, 26, 32, and 60 μM. Cytotoxic activity against the BC cell line was also observed for compound 6, with an IC50 value of 48 μM. © 2010 American Chemical Society and American Society of Pharmacognosy.en_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleOblongolides from the endophytic fungus Phomopsis sp. BCC 9789en_US
article.title.sourcetitleJournal of Natural Productsen_US
article.volume73en_US National Center for Genetic Engineering and Biotechnologyen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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