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dc.contributor.authorOunjai Kor-Anantakulen_US
dc.contributor.authorThitima Suntharasajen_US
dc.contributor.authorChitkasaem Suwanrathen_US
dc.contributor.authorPharuhas Chanprapaphen_US
dc.contributor.authorSupatra Sirichotiyakulen_US
dc.contributor.authorThawalwong Ratanasirien_US
dc.contributor.authorChutawadi Vuthiwongen_US
dc.contributor.authorAlan Geateren_US
dc.description.abstractAims: To establish the normative data distribution of nuchal translucency (NT) thickness in Thai fetuses. Methods: A cross-sectional multicenter study was conducted among 6,455 women with singleton pregnancies and gestational age between 10 and 14 weeks. For each case, the fetal crown-rump length (CRL) and NT were measured by transabdominal ultrasound. Transvaginal ultrasounds were used in poorly visualized cases. The distribution values of the NT thicknesses and their corresponding 10-mm CRL intervals between 45 and 84 mm were examined to obtain the median and 95th percentiles. Quantile regression modeling across the CRLs was performed to obtain the reference values. Results: Transabdominal ultrasound measurements were successfully done on 6,347 fetuses with 39 cases by the transvaginal route. Fetuses with CRL between 45 and 84 mm and normal outcomes made up a total of 4,352 cases. The mean (SD) gestational age, CRL and NT thickness were 12.5 (0.7) weeks, 60.2 (9.7) mm, and 1.15 (0.38) mm, respectively. The mean normal NT increased linearly with CRL. The quantile regression equation to predict the 95th percentile of the NT thickness (mm) was 0.727 + [0.017 × CRL (mm)]. Conclusions: The NT thickness in normal Thai fetuses was found to be thinner than in both Caucasian and other Asian populations. Copyright © 2010 S. Karger AG, Basel.en_US
dc.titleDistribution of normal nuchal translucency thickness: A multicenter study in Thailanden_US
article.title.sourcetitleGynecologic and Obstetric Investigationen_US
article.volume71en_US of Songkla Universityen_US Mai Universityen_US Kaen Universityen_US College of Medicineen_US
Appears in Collections:CMUL: Journal Articles

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