DSpace Collection:
http://cmuir.cmu.ac.th/jspui/handle/6653943832/7588
2024-03-03T19:45:54ZSurvey of extended spectrum beta-lactamase producing Escherichia coli in dairy farms in special region of Yogyakarta Province, Indonesia
http://cmuir.cmu.ac.th/jspui/handle/6653943832/79426
Title: Survey of extended spectrum beta-lactamase producing Escherichia coli in dairy farms in special region of Yogyakarta Province, Indonesia
Authors: Kusnul, Yuli Maulana
Abstract: Extended spectrum beta-lactamase (ESBL) E. coli has been emerged and
considered as an antimicrobial resistant evidence among human, animal and environment.
This study aims to detect the occurrence of ESBL-producing E. coli in dairy farms, and to
survey knowledge, attitude and practice of antibiotics in dairy farms. During AugustNovember 2020, total samples were collected from 93 dairy farms with history of previous
6 month-antibiotic uses in Yogyakarta province, Indonesia. Extended spectrum betalactamase (ESBL) E. coli with Antimicrobial Susceptibility Test (AST) were identified
using conventional method and Vitek-2. Knowledge, attitude and practice (KAP) were
explored by interview and observation. Among 558 samples, 11% (59) were positive with
ESBL-producing E. coli, consisting of 25% (23/93) feces, 16% (15/93) waste water, 10%
(9/93) drinking water, 5% (5/93) feed, 4% (4/93) milk and 3% (3/93) hand rinsing,
respectively. Presence of ESBL-producing E coli was identified 53.7% (50/93) in dairy
farms. From 127 ESBL-producing E. coli isolates, majority were resistant to
Trimethoprim/Sulfamethoxazole 74%, follows by Tetracycline 63% and Gentamicin 48%,
respectively. Multidrug resistant (MDR) were found 50% (63/127). Knowledge on
antibiotics of dairy farmer were found in mid-level, with the belief of “antibiotics should
be prescribed by veterinarian only”. The hygienic practice such as wash hand and clean floor before milking” are the most common practice. In addition, veterinarians, paraveterinarian and drug store were also involved in treatment practice. There is no association
between the KAP and occurrence of ESBL-Producing E. coli in dairy farms. In conclusion,
the occurrence of ESBL-Producing E. coli was found in all types of samples in dairy farms
in Yogyakarta province, Indonesia. In order to better understand the transmission, risk
factors should be further studied in this area which could benefit the national AMR
strategic plans.2021-07-01T00:00:00ZPredisposing markers for diagnosis of elephant endotheliotropic herpesvirus-hemorrhagic disease and other illness conditions
http://cmuir.cmu.ac.th/jspui/handle/6653943832/79391
Title: Predisposing markers for diagnosis of elephant endotheliotropic herpesvirus-hemorrhagic disease and other illness conditions
Authors: วรพงศ์ โกษารักษ์ Worapong Kosaruk
Abstract: The Asian elephant (Elephas maximus) serves as a keystone species, playing a crucial role in wildlife-based ecotourism in Thailand. Captive elephants, mostly privately owned and residing in tourist-oriented facilities known as "elephant camps" across Thailand, have the potential to significantly impact elephant welfare and health due to diverse management styles and activities. Various diseases afflict captive elephants, including gastrointestinal issues, lameness, eye problems, and the deadliest ailment in calves: elephant endotheliotropic herpesvirus-hemorrhagic disease (EEHV-HD). These diseases pose a global threat to elephant conservation efforts. This study delves into biomarkers linked to oxidative stress and abnormal coagulation condition in elephants, taking into account both internal factors (age, sex, and health condition) and external factors (season and the temperature-humidity index). The findings underscore the correlation between age, season, and shifts in oxidative stress markers, emphasizing the importance of considering these factors during data analysis. Additionally, the health condition of elephants exerts an impact on their oxidative status, particularly noticeable in calves afflicted with acute EEHV-HD. These calves exhibited significantly elevated concentrations of malondialdehyde, glutathione peroxidase, and catalase, along with reduced serum albumin levels when compared to their healthy counterparts. However, the association between changes in oxidative stress markers and the salivary shedding of elephant endotheliotropic herpesvirus (EEHV) remains uncertain when longitudinally monitored, possibly owing to the limited number of shedding events during the study. As for coagulation markers, calves with acute EEHV-HD displayed prolonged prothrombin and activated partial thromboplastin times, and the lowest platelet count among various illness conditions, suggesting a pathological mechanism of this virus involving both intrinsic and extrinsic coagulation pathways. Results suggest the potential utility of this biomarker in predicting and monitoring elephant diseases. The study contributes valuable insights into the alterations in oxidative stress and coagulation biomarkers, shedding light on the pathophysiology of elephant ailments. Consequently, the findings can be applied within veterinary practice as an additional analytical tool for assessing and monitoring elephant health conditions, as well as a prognostic tool for ailing elephants. Future studies should explore how these biomarkers evolve in relation to other variables, such as management practices, dietary factors, activities, social dynamics, and various environmental influences.2023-11-04T00:00:00ZEfficacy of Hydroxyapatite-based Hydrogel on Alveolar bone regeneration in post extraction socket of teeth in dogs
http://cmuir.cmu.ac.th/jspui/handle/6653943832/79340
Title: Efficacy of Hydroxyapatite-based Hydrogel on Alveolar bone regeneration in post extraction socket of teeth in dogs
Authors: Kittidaj Tanongpitchayes
Abstract: Periodontitis is the most common oral problem in geriatric and small-breed dogs.
Pathological mandibular fracture after tooth extraction can occur in dogs with moderate
to severe periodontitis as a result of extensive alveolar bone destruction. A
nanohydroxyapatite-based hydrogel (HAP hydrogel) was developed to diminish the
limitations of hydroxyapatite for post-extraction socket preservation (PSP). However, the
effectiveness of HAP hydrogel for PSP has still not been evaluated. In addition, there are
a few studies about PSP in periodontitis dogs. Consequently, the objective of this study
is to assess the effectiveness of HAP hydrogel for PSP in dogs with periodontitis. Five
dogs with periodontitis were done with unilateral 1st mandibular molar extraction. Ten
sockets were placed with HAP hydrogel. After that, intraoral radiography was applied to
follow up alveolar socket healing on the day of the operation, 2, 4, 8, and 12 weeks after
the operation. The results after comparing the day of operation and the week of follow-
ups using radiographic grading in Criteria A (p = 0.01, 0.02, 0.02 and 0.01) and Criteria
B (p = 0.03, 0.02, 0.02 and 0.01), bone height measurement (p = 0.04, 0.04, 0.02 and
0.013), and bone regeneration analysis (p = 0.04, 0.01, 0.01 and 0.004) demonstrated that
HAP hydrogel significantly enhanced socket healing at all follow-up times compared to
the day of operation. Moreover, the distribution of apatite formation on the hydrogel
surface after immersion under scanning electron microscopy with energy-dispersive X-
ray spectroscopy showed a homogeneous. Our study suggests that HAP hydrogel can be
applied as a bone substitute for PSP and has effectively enhanced socket regeneration in
dogs with periodontitis.2022-02-01T00:00:00ZA Retrospective study of fracture and dislocation patterns of Thoracic and Lumbar Vertebrae and surgical outcome in dogs and cats
http://cmuir.cmu.ac.th/jspui/handle/6653943832/79339
Title: A Retrospective study of fracture and dislocation patterns of Thoracic and Lumbar Vertebrae and surgical outcome in dogs and cats
Authors: A Dul Sangthong
Abstract: The fracture and dislocation patterns of the thoracic and lumbar vertebrae and the surgical
outcome in dogs and cats were retrospective investigated at the Small Animal Teaching
Hospital, Chiang Mai University since October 2016 to December 2019. The 913 patients
were found having traumatic injuries. There was 26.07% (238/913) of these patients had
traumatic spinal injury. There were 82.77% (197/238) had injuries at the thoracic and
lumbar areas which consisted of the dogs by 64.97% (128/197), and the cats by 35.03%
(69/197). The most common damaged location in dogs and cats was T3 - L3 (47.48%,
113/238), followed by L4 - L7 (34.87%, 83/238), S1 -S3 (16.39%, 39/238), C1 -C5
(0.84%, 2/238), and C6 - T2 (0.42%, 1/238). Luxation was the most pattern of damage
found in dogs by 37.49% followed as combined fracture and luxation 27.34%,
burst/compression 20.90%, transverse fracture 3.90%, and hyperflexion 1.56%. The
hyperextension was not found in dogs in this study. Similarly, luxation was the most
pattern of damage found in cats by 39.12%, however, burst/compression was the second
found by 27.54%, following as combined fracture and luxation 17.39%, transverse
fracture 14.49%, and hyperextension 1.44%. The hyperflexion was not found in cats in
this study. In dogs, 47 patients (36.72%) were chosen on conservative treatment whilst
21 dogs (16.40%) were performed surgery, 7 dogs (5.46%) were euthanized, 53 dogs
(41.41%) did not have any treatments at the Small Animal Teaching Hospital, Chiang
Mai University. In 69 cats, 33 cats (47.83%) were selected on conservative treatment, 6
cats (8.69%) having surgery, 9 cats (13.04%) were euthanized, and 21 cats (30.43%) did
not have any treatments at the Small Animal Teaching Hospital, Chiang Mai University.
The 21 dogs and 6 cats, who had surgical treatment, 52.38% (11/21) of the dogs and 50%
(3/6) of the cats in this study had the better outcomes in six months after the surgery.2021-02-17T00:00:00Z